The French Agency for Food, Environmental and Occupational Health & Safety (ANSES) ( 4) and the European Food Safety Authority (EFSA) have revised the nutritional guidance for vitamin D. Vitamin D bears pleiotropic functions ( 1, 2), primarily on phosphocalcic and bone homeostasis, crucial in infants ( 3). Vitamin D is a fat-soluble hormone either synthetized endogenously or from external vitamin intakes. Broadly, there is a need for harmonization of the regulation and labeling of dietary supplements and medications containing vitamin D. This case highlights the pivotal role of therapeutic education. In fact, many different medications and dietary supplements with vitamin D exist, offering various concentrations and units of measurement. They substituted the prescribed medicinal vitamin D by a dietary supplement, different in concentration and dosing, without performing the dose conversion needed. Indeed, the parents had followed the advice of their midwife. Upon detailed questioning of the parents, a vitamin D administration error has been identified. We report the case of a 3-month-old infant who suffered from severe hypercalcemia. However, vitamin D overdose can result in life-threatening hypercalcemia. Vitamin D supplementation is routinely introduced in infants, according to medical guidelines.
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